Table 4.
Details of the difficult cases a
| Case no. | Consensus diagnosis | Discordance of the original diagnosis b | Frequency of each diagnostic category c | |||
|---|---|---|---|---|---|---|
| Concordance | Minor discordance | Major discordance | Serious discordance | |||
| 86 | MALT lymphoma | Minor | 0 | 2 | 3 | 0 |
| 101 | Extranodal NK/T-cell lymphomad | Major | 0 | 1 | 3 | 0 |
| 19 | Diffuse large B-cell lymphomad | - | 4 | 0 | 3 | 0 |
| 83 | Lymphoplasmacytic lymphoma | Minor | 0 | 2 | 2 | 0 |
| 32 | Diffuse large B-cell lymphoma | - | 3 | 0 | 2 | 0 |
| 82 | Lymphoplasmacytic lymphoma | Minor | 2 | 4 | 1 | 0 |
| 113 | Peripheral T-cell lymphoma, NOS | Major | 1 | 2 | 1 | 0 |
| 78 | Follicular lymphoma | - | 3 | 2 | 1 | 0 |
| 36 | Diffuse large B-cell lymphoma | - | 0 | 5 | 0 | 0 |
| 100 | Extranodal NK/T-cell lymphomad | Minor | 0 | 5 | 0 | 0 |
| 93 | Mixed cellularity classical HL | Minor | 1 | 5 | 0 | 0 |
| 76 | Follicular lymphoma | - | 3 | 4 | 0 | 0 |
| 109 | Nodular sclerosis classical HL | Major | 3 | 4 | 0 | 0 |
| 98 | Nodal marginal zone lymphoma | - | 3 | 3 | 0 | 0 |
| 84 | Lymphocyte-rich classical HL | Minor | 1 | 2 | 0 | 0 |
| 91 | Mixed cellularity classical HL | Minor | 3 | 2 | 0 | 0 |
| 62 | Diffuse large B-cell lymphomad | - | 3 | 2 | 0 | 0 |
| 116 | T lymphoblastic lymphoma | - | 3 | 2 | 0 | 0 |
| 23 | Diffuse large B-cell lymphoma | - | 1 | 1 | 0 | 0 |
| Total | 23 | 30 | 11 | 0 | ||
aDifficult cases were cases that at least 40% of hematopathologists (participants) made discordant diagnoses.
bOriginal diagnoses, initially made by attending pathologists in clinical services, were also categorized into 4 categories by comparing to the consensus diagnoses. Blanks represent “concordance”.
cPlease see the description of each diagnostic category in Table 1.
dCases that consensus diagnoses could not be reached at the initial meeting and additional investigations were performed before reaching the consensus diagnoses.