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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Curr Opin Neurobiol. 2014 Feb 16;26:132–141. doi: 10.1016/j.conb.2014.01.015

Fig. 2. Subtypes of progenitor cells in the developing neocortex.

Fig. 2

(A) Coronal hemisection of the developing brain. The neocortex (NCx), the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the preoptic area (POA) are indicated. The blue arrow shows the migration route of excitatory neurons from the ventricular zone into the developing cortical wall. (B) Enlargement of the region boxed in (A) indicating different progenitor types. Neuroepithelial cells (NE) are present early in development and give rise to radial glial cells (RGCs). RGCs self-renew and give rise to neurons (N). RGCs also generate intermediate progenitors (IPCs) and short neural progenitors (SNPs), which divide further to generate neurons. In addition, RGCs give rise to basal radial glial cells (bRGCs), which generate via IPs additional neurons. At the end of neurogenesis, RGCs and bRGCs transform into astrocyte progenitors, which then generate astrocytes (A).