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. Author manuscript; available in PMC: 2015 Sep 8.
Published in final edited form as: Cancer Cell. 2014 Sep 8;26(3):390–401. doi: 10.1016/j.ccr.2014.07.023

Figure 3. Transplanted tumors and genomic instability in NOS.

Figure 3

(A) Photos of representative nude mice (top left) and subcutaneous tumors (bottom left) obtained from the mice 14 days after a single s.c. injection with the NOS-T12 cell line into their flanks and H&E-stained section of primary OS T12 tumor (top right) and transplanted tumors (bottom right) derived from the injected mice. Scale bars, 50 μm.

(B) Representative spectral karyotyping (SKY) evaluation of harvested cells from NOS-T12 cell line.

(C) Summary of SKY results for the indicated tumors.

(D) Summary of percentages of gains (positive axis) and losses (negative axis) for chromosomes 1–19, as determined by analysis of copy number variation (CNV), compared tumor to non-tumor controls using whole genome sequencing (CNV-seq).

See also Figure S3.

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