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. 2014 Sep 10;4:6056. doi: 10.1038/srep06056

Figure 1. Live cell imaging of different phases during the cell adhesion and spreading process.

Figure 1

(A) Initial stage of cell adhesion and intracellular distribution and organization between ACTIN and PIP2 (10 min). (B) Translocation of PIP2 domains towards the cell protrusions (30 min). (C) Cell spreading process and PIP2 nano-domains accumulations in the focal adhesion points, followed by actin fibers (1 h). (D) PIP2 and ACTIN interactions during the cell spreading process (16 h). Scale bar: 5 μm.