Skip to main content
. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Gene Ther. 2014 Jul 17;21(9):840–848. doi: 10.1038/gt.2014.64

Figure 6. Sod3 gene transfer reduces the inflammation and enhances the energy expenditure.

Figure 6

Animals were sacrificed at the end of 8 week feeding and tissue from white adipose tissue and liver were collected for RNA isolation. mRNA levels of selected gene were quantified by Real Time PCR. (a) Relative mRNA levels of inflammation related genes in adipose tissue; (b) Relative mRNA levels of anti-inflammatory genes in adipose tissue; (c) Relative mRNA levels of genes involved in de novo lipogenesis in the liver; (d) Relative mRNA levels of genes involved in lipolysis and energy metabolism in the liver; (e) Relative mRNA levels of genes involved in glucose metabolism in the liver. (□), animals fed a regular Chow; ( Inline graphic), high fat diet fed mice injected with pLIVE-SEAP; (■), high fat diet-fed mice injected with pLIVE-SOD3. Data represent mean ± SEM (n=5). * p<0.05 compared with chow mice; # p<0.05 compared with pLIVE-SEAP injected animals.