. Author manuscript; available in PMC: 2014 Sep 10.

Published in final edited form as: Breast Cancer Res Treat. 2009 Nov 24;121(3):727–735. doi: 10.1007/s10549-009-0590-z

Table 3.

Expression of TGF-β markers by age among 623 breast cancer cases participating in the Polish Breast Cancer Study

	Intracellular-TGF-β1			Extracellular-TGF-β1			TGF-β2			TGF-β3			TGF-βR2			Phospho-SMAD2

	N	%	P value	N	%	P value	N	%	P value	N	%	P value	N	%	P value	N	%	P value
Overall Positive	198	32		485	78		564	91		580	93		450	72		378	61
Age
<40 (N = 32)	7	22		28	88		27	84		31	97		28	88		27	84
40–49 (N = 170)	43	25		142	84		152	89		159	94		138	81		120	71
50–59 (N = 213)	80	38		170	80		198	93		203	95		164	77		135	63
60–69 (N = 144)	41	28		94	65		126	88		130	90		88	61		59	41
70+ (N = 64)	27	42	0.04^*	51	80	0.002^*	61	95	0.16^**	57	89	0.22^**	32	50	2.31E-07^**	37	58	7.53E-08^*
Age (mean)
Negative	54.5			57.2			53.4			58.2			59.4			57.8
Positive	56.2		0.06^***	54.5		0.005^***	55.2		0.20^***	54.8		0.05^***	53.4		8.24E-11^***	53.3	1.33E-08^***

%, percent positive tumors

P value for χ² test

^**

P value for Fisher’s exact test

^***

P value for t test