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. 2014 Jun 30;118(29):16199–16208. doi: 10.1021/jp5034068

Figure 3.

Figure 3

Hydrodynamic size and aggregation behavior of 5 nm AuNPs in water and serum media. (A) Continuous photon correlation spectroscopy histogram of 5 nm AuNPs in water at 37 °C; the inset shows the AuNP solution being measured. (B) TEM image shows individually dispersed AuNPs with a core size of 5 nm. (C) Hydrodynamic size of 5 nm AuNPs increases when exposed to serum, as is evident from the histogram; the inset shows the AuNP solution being measured. (D) TEM image shows an increased core size of AuNPs, and the data corroborates with the hydrodynamic data. These data show that both the hydrodynamic and core size of the AuNPs are dependent of the media to which they are exposed.