Table 1.

Phosphorylation site motifs for p53.

P−3	P−2	P−1	pS/pT	P+1	P+2	P+3	Kinases	Consensus Motif	Ref.
E	P	Q	S6	D	P	S	JNK2, CK1δ	P-X-S/T-P	[6,7]
S	D	P	S9	V	E	P	CK1ε	pS-X-X-S/T	[6,7]
P	P	L	S15	Q	E	T	CDK5, mTOR, ATM	P-L-S/T-P (CDK) D-S/T-Q-E (ATM)D	[14,15]
S	Q	E	T18	F	S	D	Chk2, TTK, VRK1		[14,15]
E	T	F	S20	D	L	W	Chk2, Plk3	T-X-S/T-X-X-W (Chk2)	[14,15]
N	V	L	S33	P	L	P	Cdk5/7/9, GSK3β, p38K	P-L-S/T-P (CDK)	[6,7]
P	L	P	S37	Q	A	M	ATR, PRAK	L-P-S/T-Q-A (ATR)	[6,7]
L	M	L	S46	P	D	D	Cdk5, p38K, PKC	P-L-S/T-P (CDK)	[20]
Q	W	F	T55	E	D	P	ERK2, TAF1		[21]
A	A	P	T81	P	A	A	JNK2	P-X-S/T-P	[6,7]
S	V	P	S99	Q	K	T	ATM, ATR	V-P-S/T-Q (ATR)	[6,7]
Y	Q	G	S106	Y	G	F	Aurora A		[6,7]
N	N	T	S313	S	S	P	Chk1/2		[6,7]
N	T	S	S314	S	P	Q	Chk1/2	T-X-S/T (Chk2)	[6,7]
T	S	S	S315	P	Q	P	STK15, Cdk9, CDK2	P-L-S/T-P (CDK)	[24,25]
P	G	G	S362	R	A	H	IKK2B		[6,7]
R	A	H	S366	S	H	L	IKK2, Chk2		[6,7]
K	G	Q	S376	T	S	R	PKC, GSK3β	R-K/R-X-S/T-X-K-K/R (PKC)	[25,26]
G	Q	S	T377	S	R	H	Chk1/2		[6,7]
Q	S	T	S378	R	H	K	Chk1/2, PKC	R-K/R-X-S/T-X-K-K/R (PKC)	[6,7]
M	F	K	T387	E	G	P	Chk1		[6,7]
G	P	D	S392	D			Cdk9, PKR, FACT		[30]
W	V	D	S149	T	P	P	CSN		[22,23]
V	D	S	T150	P	P	P	CSN		[22,23]
P	P	G	T155	R	V	R	CSN		[22,23]
E	R	C	S183	D	S	D	Aurora B	R/K-X-S/T (Aurara B)	[68]
D	R	N	T211	F	R	H	Aurora B	R/K-X-S/T (Aurara B)	[68]
F	R	H	S215	V	V	V	STK15, Aurora B	R/K-X-S/T (Aurara B)	[32]
G	R	N	S269	F	E	V	Aurora B	R/K-X-S/T (Aurara B)	[68]