Table 2.

TNF-α inhibitory activity (IC₅₀) of SMs, (R/S) NRG and SNRGMs on LPS-stimulated hPBMC from two different normal donors.

Treatment	IC50 (μg/mL)
	Donor A	Donor B
SMs	200 *	>200 **
NRG	8.7	33.6
SNRGMs ***	1.9	2.8
Fold increase	4.6	12.0

* 48.7% inhibition at 200 μg/mL; ** 20.2% inhibition at 200 μg/mL; *** IC₅₀ referred to NRG contained in SNRGMs.