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. 2014 Aug 6;15(8):13637–13648. doi: 10.3390/ijms150813637

Figure 3.

Figure 3

Celastrol suppressed carrageenan-induced inflammation. The effect of vehicle (VEH, 5% PEG/5% Tween-80 in saline, 10 mL/kg, i.p.) and celastrol (CEL, 0.3 mg/kg, 10 mL/kg, i.p.) on the mRNA expressions of (A) TNF-α; (B) IL-6; and (C) IL-1β in the paw tissues of carrageenan injected mice (close bars). *** p < 0.001 vs. non-carrageenan injection (CT, open bars); # p < 0.05, ## p < 0.01, ### p < 0.001 vs. VEH, one-way ANOVA with Bonferroni’s multiple comparison test. n = 6.