Table 3.
Registered clinical trials on mesenchymal stem cells for retinal diseases. Information obtained from ClinicalTrials.gov.
| Identifier | Country | Study | Phase of Trial | Intervention | Disease | Cells |
|---|---|---|---|---|---|---|
| NCT01914913 | India | Clinical study to evaluate safety and efficacy of stem cell Therapy in Retinitis Pigmentosa | Phase 1, Phase 2 | Transfer of mesenchymal stem cell | RP | Bone marrow and umbilical cord derived mesenchymal stem cell |
| NCT01068561 NCT01560715 | Brazil | Autologous bone marrow-derived stem cells transplantation for retinitis pigmentosa | Phase 1, Phase 2 | Intravitreal injection | RP | Autologous bone marrow stem cells |
| NCT01531348 | Thailand | Feasibility and safety of adult human bone marrow-derived mesenchymal stem cells by intravitreal injection in patients with retinitis pigmentosa | Phase 1 | Intravitreal injection | RP | Adult human bone marrow-derived mesenchymal stem cells |
| NCT01736059 | USA | Clinical trial of autologous intravitreal bone-marrow CD34+ stem cells for retinopathy | Phase 1 | Intravitreal injection | Dry AMD; DR; RVO; RP; Hereditary macular degeneration | CD34+ bone marrow stem cells |
| NCT01920867 | USA | Stem cell ophthalmology treatment study | Retrobulbar Subtenon Intravenous Intravitreal Intraocular | Retinal disease; macular degeneration; hereditary retinal Dystrophy optic nerve disease; glaucoma | Autologous bone marrow derived stem cells |
AMD, Age-related Macular Degeneration; DR, diabetic retinopathy; RVO, retinal vein occlusion.