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(A) Biosynthetic gene cluster for methylated ditryptophan CDPs; (B) LCMS chromatogram showing the single product of the CDPS Amir_4627; and (C) Overview of the biosynthetic pathway leading to singly and doubly methylated ditryptophan CDPs in A. mirum. Adapted from [29] with permission from American Chemical Society, copyright 2013. Investigated CDO (cyclic dipeptide oxidase)-modifications are shown in red.
