FIG. 4.
Hypoxia imaging methods and the type of information provided by each modality. BOLD MRI, blood oxygen level-dependent magnetic resonance imaging; DCE-MRI, dynamic contrast-enhanced magnetic resonance imaging; EPR, electron paramagnetic resonance; HIF-1α, hypoxia-inducible factor 1α; NIRS, near-infrared spectroscopy; OMRI, Overhauser-enhanced MRI; PALI, photoacoustic lifetime imaging; PAT, photoacoustic tomography; PET, positron emission tomography; PIMO, pimonidazole.