Table 3. Correlation of magnetization transfer ratios across regions of interest with age.
| Region | HC (N = 31) | MDD (N = 28) | ||
|---|---|---|---|---|
|
|
|
|||
| r | P-value | r | P-value | |
| hCaud_R | 0.024 | 0.896 | −0.592 | 0.001 |
| hCaud_L | −0.105 | 0.573 | −0.456 | 0.015 |
| Thalamus_R | −0.285 | 0.120 | −0.323 | 0.093 |
| Thalamus_L | −0.276 | 0.133 | −0.220 | 0.261 |
| LOFC_R | −0.044 | 0.813 | −0.053 | 0.791 |
| LOFC_L | −0.461 | 0.009 | 0.005 | 0.980 |
| AC_R | −0.183 | 0.326 | −0.224 | 0.252 |
| AC_L | −0.227 | 0.220 | −0.465 | 0.013 |
| FWM_R | −0.279 | 0.129 | −0.493 | 0.008 |
| FWM_L | −0.511 | 0.003 | −0.534 | 0.003 |
| Putamen_R | −0.509 | 0.003 | −0.557 | 0.002 |
| Putamen_L | −0.416 | 0.020 | −0.586 | 0.001 |
| GP_R | −0.203 | 0.272 | −0.491 | 0.008 |
| GP_L | −0.114 | 0.543 | −0.202 | 0.302 |
| DLPFC_R | −0.470 | 0.008 | −0.431 | 0.022 |
| DLPFC_L | −0.276 | 0.132 | −0.441 | 0.019 |
Abbreviations: AC, anterior cingulate; DLPFC, dorsal lateral prefrontal cortex; FWM, periventricular frontal white matter; GP, globus pallidus; HC, healthy controls; hCaud, head of caudate nucleus; L, left; LOFC, lateral orbitofrontal cortex; MDD, patients with major depression; R, right. Bold values indicate statistically significant results.