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. Author manuscript; available in PMC: 2014 Sep 10.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jan 20;(1):CD007130. doi: 10.1002/14651858.CD007130.pub2
Methods RCT parallel group
Participants n = 15 patients in Home-based CR group; n = 14 pts in Centre-based CR group; diagnosis: heart failure; case mix: CHF class II or III NYHA with ischemic or idiopathic dilated cardiomyopathy; mean age 52 (SD 8.5); 76% male
Inclusion: heart failure of >3 month duration
Exclusion: valvular heart disease, exercise-induced cardiac arrhythmias, symptomatic myocardial ischemia within 3 months, taking beta-blockers
Interventions Home-based CR (intervention):
Exercise: Total duration: 12 weeks; frequency: 3 sessions/wk; duration: 45 mins/session (including warm-up, cool-down, recovery); intensity: up to 60% peak heart rate (RPE 1216); modality: walking; follow-up logs completed daily/returned biweekly. Weekly phone calls from staff monitoring adherence & progress, monthly phone calls from patients for control purposes
Other: not reported
Centre-based CR (control):
Exercise: Total duration: 12 weeks; frequency: 3 sessions/wk; duration: 45 mins/session (including warm-up, cool-down, recovery); intensity: 60% peak heart rate; modality: walking on a treadmill. Supervised
Other: not reported
Outcomes (primary and secondary outcomes not distinguished) exercise capacity (ml/kg/min), resting BP systolic & diastolic BP, adherence, dropouts; additionally data on mortality obtained by personal contact
Follow up 12 weeks post randomisation
Subgroup analyses No subgroups described or reported
Country & settings Turkey, single centre
Notes Additional data on mortality obtained by personal contact
Risk of bias
Bias Authors’ judgement Support for judgement
Adequate sequence generation? Unclear risk Not reported
Allocation concealment? Unclear risk Not reported
Blinding?
All outcomes
Unclear risk Not reported
Incomplete outcome data addressed?
All outcomes
Low risk
Free of selective reporting? Low risk All outcomes described in the methods section are reported in the results
Groups balanced at baseline? Low risk Among patients who completed the study, no differences in demographic characteristics were seen between the 2 study groups after randomization (p>0.05). ”
Intention to treat analysis? High risk ITT not reported
Groups received same intervention? Low risk We chose lower intensity …training prescriptions in the HETG to avoid any adverse occurrences and also in the SETG to provide comparable training intensity levels between 2 groups. ”