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. Author manuscript; available in PMC: 2014 Sep 10.
Published in final edited form as: Cochrane Database Syst Rev. 2006 Oct 18;(4):CD001561. doi: 10.1002/14651858.CD001561.pub2
Methods High risk groups identified from epidemiological surveys, opportunistic screening, volunteers.
Randomisation by individual, stratified by sex, centre and OGTT result
Participants Overweight or with family history of type 2 diabetes men and women aged 40-64 years with impaired glucose tolerance
N=523
Interventions Nutritionist delivered individual and group dietary advice. Weight goal established with physician and nutritionist and reguar assessment. Supervised exercise. Each person had 7 sessions in the first year and one session every 3 months subsequently
Outcomes No clinical events outcomes. Development of diabetes, weight, diet, exercise, waist circumference, glucose, insulin, cholesterol, HDL, triglycerides, systolic and diastolic blood pressure. Follow up reported end of year 1
Notes Study planned for 6 years, recruited 1993 to 1998. In March 2000 study stopped on basis of results regarding reduction in incidence in diabetes in treatment group