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. Author manuscript; available in PMC: 2014 Sep 10.
Published in final edited form as: Cochrane Database Syst Rev. 2006 Oct 18;(4):CD001561. doi: 10.1002/14651858.CD001561.pub2
Methods Primary care practices in urban area
Randomisation by household
Participants Men and women, mean age 49 years (35-64)
No risk screening
N=11,090
Interventions Diet, smoking advice, weight control, alcohol advice, exercise, protocols for management of high blood pressure and raised blood cholesterol vs. usual care.
Duration 3 years
Outcomes Total mortality and CHD mortality
Systolic blood pressure, diastolic blood pressure, blood cholesterol, smoking prevalence, BMI
Notes Changes in diet and small changes in blood cholesterol, blood pressure and body mass index. No effect on smoking prevalence. Concluded that primary prevention programmes were able to achieve benefits which were real but must be weighted against the costs in relation to other priorities. Study was not designed to examine mortality effects but those randomised to health checks in years 1 to 3 were considered to be intervention group and those randomised to checks in year 4 were the control group. Deaths up to year 4 were compared