. Author manuscript; available in PMC: 2014 Sep 15.

Published in final edited form as: Clin Cancer Res. 2014 Feb 3;20(6):1656–1665. doi: 10.1158/1078-0432.CCR-13-2506

Table 4.

Cancer-related exome variants seen exclusively in sensitive and resistant squamous cell carcinomas

Gene	Description	Chromosome	Nucleotide change	Amino acid change
Nonsynonymous	SNPs present in both sensitive tumors, but not in resistant tumors
ABCC11	ATP-binding cassette, subfamily C (CFTR/MRP), member 11	16	T>A	N1277Y
ACIN1	Apoptotic chromatin condensation inducer 1	14	T>C	N20S
FAT1	FAT tumor suppressor homolog 1 (drosophila)	4	G>A	A131V
ROBO3	Roundabout, axon guidance receptor, homolog 3 (drosophila)	11	G>A	R416H
Nonsynonymous	SNPs present in all resistant tumors, but not in sensitive tumors
CDH23	Cadherin-related 23	10	A>G	N1351D
HCLS1	Hematopoietic cell-specific Lyn substrate 1	3	C>T	E361K