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. Author manuscript; available in PMC: 2015 Feb 6.
Published in final edited form as: Nat Med. 2014 Aug 6;20(8):870–880. doi: 10.1038/nm.3651

Figure 2.

Figure 2

Types of DNA damage in the aging genome that may affect stem cell function. Products of and effectors of DNA damage known to increase and accumulate during aging are shown, along with their effects on stem cell aging. CPD, cyclobutane pyrimidine dimer; DSB, double-strand break.