Table II.
Isothermal titration calorimetry (ITC) results for wildtype and K24N mutant.
p53TAD | K24N | |
---|---|---|
ΔG | −8.93 (0.17) | −9.12 (0.13) |
ΔH | −10.90 (0.83) | −10.50 (0.29) |
TΔS | −1.96 (0.77) | −1.38 (0.37) |
Values are in kcal/mol. The values for p53TAD are the averages and standard deviations (in parentheses) from two separate protein preparations with three repeats each. The averages and standard deviations (in parentheses) for K24N are based on three ITC measurements performed on the same protein preparations.