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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Neurooncol. 2014 May 4;119(1):27–35. doi: 10.1007/s11060-014-1458-6

Figure2. Immunofluorescence staining shows overexpression of Separase in glioblastoma tissue sections.

Figure2

Separase staining (green) showed a higher percentage of positive cells, not all of which were proliferative (shown by Ki-67 staining in red). Normal brain sections stained for the same markers showed only background level of staining. Pediatric glioblastoma shows clusters of positive Separase expression in non-proliferating cells (bottom panel).