Fig 3.

Preclinical study ¹³C MR data. (A) Representative hepatic ¹³C spectrum acquired after 6 hours of [2-¹³C]-glycine infusion. (B) Regions of the ¹³C spectrum showing resonances from [2-¹³C]-glycine and ¹³C-labeled GSH from rats in each of the three study groups. (C) Time course of hepatic ¹³C-labeled GSH concentration in the experimental groups. (D) Mean concentrations of ¹³C-labeled and total GSH in the experimental groups at the end of the 6.5-hour experiment. (E and F) Time courses of hepatic [2-¹³C]-glycine and [2-¹³C]-serine concentration in the experimental groups.