Table 2.
Baseline Demographic and Clinical Characteristics of Patients with Familial CCM1-CHM Enrolled in Project 1.
| Baseline Characteristics | Value |
|---|---|
|
| |
| Female gender, No. (%) | 123 (65) |
|
| |
| Age at enrollment, mean (SD), year | 39.1 (19.7) |
|
| |
| Age at diagnosis mean (SD), year | 31.8 (19.3) |
|
| |
| Symptomatic at presentation, No. (%) | 122 (64) |
| Hemorrhage | 46 (24) |
| Seizure | 46 (24) |
| NH-FND | 7 (4) |
| Headache | 41 (22%) |
|
| |
| Ever symptomatic, No. (%) | 167 (88) |
| Hemorrhage | 63 (33) |
| Seizure | 59 (31%) |
| NH-FND | 9 (5) |
| Headache | 101 (53) |
|
| |
| Comorbidities | |
| Obesity | 68 (38) |
| Hypertension | 56 (29) |
| Hyperlipidemia | 98 (52) |
| Depression/Anxiety | 34 (18) |
| Diabetes | 18 (9) |
| Arthritis | 22 (12) |
| Hypothyroidism | 13 (7) |
Abbreviations: CCM1-CHM, cerebral cavernous malformations type 1, common Hispanic mutation, NH-FND, Nonhemorrhagic Focal Neurological Deficit