Table 1. Socio-demographic and psycho-immunologic data of the healthy control subjects, Crohn’s disease (CD) and irritable bowel syndrome (IBS) patients who participated to the study.
| Controls | Crohn’sDisease (CD) | Irritable BowelSyndrome (IBS) | p value | |
| Total number of subjects | 26 | 21 | 26 | |
| Mean age, year ± SD | 36±10 | 40±11 | 38±11 | NS CD or IBS vs controls |
| Sex, M/F | 8/18 | 9/12 | 7/19 | |
| BMI (Kg/m2) | 23±3.5 | 22±4.3 | 22±5.2 | NS CD or IBS vs controls |
| Mean duration of disease,year (range) | - | 13.4 (1–28) | 10.3 (1–31) | |
| Localization of Crohn’s disease according to Montreal classification | Ileal: | |||
| L1B1: n = 3 | ||||
| L1B2: n = 3 | ||||
| B1pB3: n = 1 | ||||
| Colonic: | ||||
| L2B1: n = 6 | ||||
| L2B1pB3: n = 2 | ||||
| Ileocolonic: | ||||
| L3B1: n = 2 | ||||
| L3B2: n = 2 | ||||
| L3B2pB3: n = 2 | ||||
| Inflammatory markers (circulating levels) | ||||
| CRP level (mg/l) | <4 | <5 | <5 | NS CD or IBS vs controls |
| Perceived abdominal visceral pain | ||||
| VAS | 0.30±0.34 | 1.28±0.38 | 2.19±0.34 | IBS vs controls p<0.001 |
| Mood variables | ||||
| State-Anxiety | 31±1.90 | 39±2.15 | 41±1.91 | CD vs controls p<0.05; IBS vs controls p<0.001 |
| Depressive symptomatology | 8.94±1.39 | 13.68±1.58 | 19.51±1.40 | CD vs controls p = 0.07; IBS vs controls p<0.001; IBS vs CD p<0.05 |