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. 2014 Sep 10;9(9):e105406. doi: 10.1371/journal.pone.0105406

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© 2014 Zhu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) . (B) . (C) Average cell speed , average -component (resp. -component) of the cell velocity (resp. ) for a shearotactic signal pointing toward the positive direction. At both ends of the calcium concentration range considered, the shearotactic efficiency is extremely poor as attested by the values of and . A high shearotactic efficiency is achieved for calcium concentrations in the 1–3 mM range. For the speed, a clear maximum is attained for a concentration of 3 mM. The optimal shear stress level of 0.18 Pa is considered for the seven different values of the external calcium concentration. A log-scale is used for the calcium concentration on the -axis and for each value of [Ca²⁺]_ext the averaging process is based on a population comprising between 60 to 135 individual tracked cells for a duration of 1,200 seconds and with a sampling time of 15 seconds. Cells are crawling over a plastic hydrophobic surface.

Inline graphic — (A) . (B) . (C) Average cell speed , average -component (resp. -component) of the cell velocity (resp. ) for a shearotactic signal pointing toward the positive direction. At both ends of the calcium concentration range considered, the shearotactic efficiency is extremely poor as attested by the values of and . A high shearotactic efficiency is achieved for calcium concentrations in the 1–3 mM range. For the speed, a clear maximum is attained for a concentration of 3 mM. The optimal shear stress level of 0.18 Pa is considered for the seven different values of the external calcium concentration. A log-scale is used for the calcium concentration on the -axis and for each value of [Ca²⁺]_ext the averaging process is based on a population comprising between 60 to 135 individual tracked cells for a duration of 1,200 seconds and with a sampling time of 15 seconds. Cells are crawling over a plastic hydrophobic surface.