Table 3. Characteristics of infectors in 21 transmission clusters identified by phylogenetic reconstruction based on pol sequences.
Cluster No. | Patient No. | Risk Factors | Sex | Age | Location | Genotype | CD4 | PVL | Drug resistant mutations (HIVdb) | |||
PI Major | PI Minor | NRTI | NNRTI | |||||||||
1 | YN178 | IDU | Male | 76 | Jinghong | B’/C URF | 341 | 7526 | ||||
YN218 | Heterosexual | Male | 76 | Jinghong | B’/C URF | 564 | 208505 | |||||
YN506 | Heterosexual | Male | 66 | Jinghong | B’/C URF | 339 | 12951 | |||||
YN507 | Heterosexual | Female | 64 | Jinghong | B’/C URF | 490 | 1870 | |||||
YN509 | Heterosexual | Female | 68 | Jinghong | B’/C URF | 479 | 140719 | |||||
YN513 | Heterosexual | Female | 64 | Jinghong | B’/C URF | 432 | 12900 | |||||
YN523 | Heterosexual | Male | 80 | Jinghong | B’/C URF | 206 | 10530 | |||||
2 | YN261 | Heterosexual | Female | 48 | Jinghong | CRF07_BC | 254 | 20820 | ||||
YN475 | Heterosexual | Male | 47 | Jinghong | CRF07_BC | 135 | 128310 | |||||
3 | YN163 | Uncertain | Male | 27 | Jinghong | CRF08_BC | 967 | 5450 | ||||
YN164 | Uncertain | Male | 31 | Jinghong | CRF08_BC | 191 | 100560 | |||||
4 | YN141 | Heterosexual | Female | 62 | Jinghong | CRF08_BC | 651 | 5563 | V179T | |||
YN183 | Heterosexual | Female | 61 | Jinghong | CRF08_BC | 176 | 12525 | V179T | ||||
YN500 | Heterosexual | Male | 76 | Jinghong | CRF08_BC | 168 | 19633 | V106IV, V179T | ||||
5 | YN040 | Heterosexual | Male | 27 | Menghai | CRF08_BC | 249 | 156805 | V90I | |||
YN124 | Heterosexual | Female | 49 | Menghai | CRF08_BC | 190 | 44594 | V90I | ||||
YN190 | Heterosexual | Male | 38 | Menghai | CRF08_BC | 273 | 1050 | V90I | ||||
YN588 | Heterosexual | Male | 32 | Menghai | CRF08_BC | 319 | 32013 | V90I | ||||
YN590 | Heterosexual | Female | 24 | Menghai | CRF08_BC | 564 | 108756 | V90I | ||||
6 | YN155 | Heterosexual | Female | 41 | Jinghong | CRF08_BC | 444 | 324 | ||||
YN493 | Heterosexual | Female | 33 | Jinghong | CRF08_BC | 579 | 167500 | |||||
7 | YN102 | Heterosexual | Male | 39 | Jinghong | CRF08_BC | 191 | 4108 | E138A | |||
YN103 | Heterosexual | Female | 27 | Jinghong | CRF08_BC | 454 | 654043 | |||||
8 | YN266 | Heterosexual | Female | 28 | Jinghong | CRF08_BC | 440 | 1527400 | ||||
YN522 | Heterosexual | Female | 25 | Jinghong | CRF08_BC | 840 | 2579 | |||||
9 | YN584 | Heterosexual | Male | 28 | Puer | CRF08_BC | 521 | <50 | E138A | |||
YN585 | Heterosexual | Male | 29 | Puer | CRF08_BC | 461 | <50 | E138A | ||||
10 | YN106 | IDU | Male | 48 | Jinghong | CRF08_BC | 53 | 1665004 | ||||
YN524 | Heterosexual | Female | 35 | Mengla | CRF08_BC | 1178 | 1320 | |||||
11 | YN123 | Heterosexual | Female | 23 | Menghai | CRF08_BC | 400 | 2095 | ||||
YN569 | Heterosexual | Male | 25 | Menghai | CRF08_BC | 392 | 3328 | |||||
YN570 | Heterosexual | Female | 23 | Menghai | CRF08_BC | 139 | 4114 | |||||
12 | YN251 | IDU | Male | 28 | Jinghong | CRF08_BC | 462 | 1871 | ||||
YN464 | Heterosexual | Female | 16 | Jinghong | CRF08_BC | 495 | 25533 | |||||
13 | YN127 | Heterosexual | Male | 28 | Jinghong | CRF08_BC | 1073 | 16700 | ||||
YN468 | MSM | Male | 25 | Jinghong | CRF08_BC | 515 | 2301 | |||||
YN470 | MSM | Male | 38 | Jinghong | CRF08_BC | 387 | 40423 | |||||
YN473 | MSM | Male | 25 | Jinghong | CRF08_BC | 350 | 38508 | |||||
YN529 | Heterosexual | Male | 36 | Jinghong | CRF08_BC | 623 | 16965 | |||||
14 | YN136 | Heterosexual | Female | 20 | Menghai | CRF08_BC | 396 | 1068 | Q58E, T74S | |||
YN196 | Heterosexual | Male | 29 | Menghai | CRF08_BC | 387 | 1370 | Q58E, T74S | ||||
YN577 | Heterosexual | Male | 29 | Menghai | CRF08_BC | 594 | 17220 | Q58E, T74S | ||||
15 | YN239 | Heterosexual | Male | 28 | Jinghong | CRF08_BC | 355 | 738 | V90I, V179D | |||
YN295 | IDU | Male | 31 | Jinghong | CRF08_BC | 523 | 1204 | V90I, V179D | ||||
YN297 | IDU | Male | 33 | Jinghong | CRF08_BC | 619 | 1109 | V90I, V179D | ||||
YN294 | IDU | Male | 30 | Jinghong | CRF08_BC | 604 | 779 | V90I, V179D | ||||
16 | YN119 | Heterosexual | Male | 19 | Jinghong | CRF08_BC | 309 | 131000 | ||||
YN120 | IDU | Male | 23 | Jinghong | CRF08_BC | 351 | 790690 | Y181HY | ||||
YN252 | Heterosexual | Male | 42 | Jinghong | CRF08_BC | 337 | 1202 | |||||
17 | YN195 | Heterosexual | Male | 29 | Menghai | CRF01_AE | 40 | 207798 | L33F* | |||
YN274 | IDU | Male | 23 | Jinghong | CRF01_AE | 1618 | 318 | L33F* | ||||
18 | YN193 | Heterosexual | Female | 24 | Menghai | CRF01_AE | 58 | 213587 | A98G | |||
YN194 | Heterosexual | Male | 26 | Menghai | CRF01_AE | 1042 | 56 | A98G | ||||
YN563 | Heterosexual | Male | 35 | Menghai | CRF01_AE | 36 | 6241 | A98G | ||||
19 | YN185 | Heterosexual | Male | 59 | Jinghong | CRF01_AE | 86 | 84786 | L33F* | |||
YN564 | Heterosexual | Female | 26 | Menghai | CRF01_AE | 195 | 132000 | L33F* | ||||
20 | YN219 | Heterosexual | Female | 35 | Jinghong | CRF01_AE | 652 | 2450 | ||||
YN223 | Heterosexual | Male | 36 | Jinghong | CRF01_AE | 138 | 10400 | |||||
21 | YN259 | Heterosexual | Male | 26 | Menghai | CRF01_AE | 480 | 258460 | ||||
YN576 | Heterosexual | Female | 22 | Menghai | CRF01_AE | 711 | 28202 |