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. Author manuscript; available in PMC: 2014 Sep 10.
Published in final edited form as: Sci Signal. 2013 Apr 2;6(269):pl1. doi: 10.1126/scisignal.2004088

Fig. 5. The Mutations tab.

Fig. 5

To generate these results, the query was limited to mutations for ERBB2 in the indicated cancer study. Four of the 10 ERBB2 mutations in colorectal cancer occur in a hotspot in the kinase domain. (A) The graphical view shows the Pfam protein domains and the positions of specific mutations. The length of the line connecting the mutation annotation to the protein is indicative of the number of samples that have the mutation. The most recurrent mutations are labeled in the graphical view. (B) The tabular view provides additional information about all mutations in each query gene.