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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Pathog Dis. 2014 May 8;72(1):10–18. doi: 10.1111/2049-632X.12167

Fig. 3.

Fig. 3

iglE Francisella tularensis ssp. novicida is defective for intra-macrophage replication. Francisella tularensis ssp. novicida strains U112 (WT) and KKF194 (ΔiglE) either without plasmid or carrying plasmids pKEK1355 (expresses IglE-FLAG) or pKEK1368 (expresses IglEC22G-FLAG) were inoculated at an MOI of c. 10 : 1 into J774 cells, and intracellular bacteria were enumerated at 3, 24, and 48 h. The assay was performed in triplicate. **P < 0.01;***P < 0.001.