Table 2.
Gene name | dbSNPa | Nucleotide/amino acid change | MAFb | χ 2c | P valuec | MAFb | χ 2c | P valuec |
---|---|---|---|---|---|---|---|---|
BC patients | Controls | |||||||
GSTM1 | – | Deletion | – | – | ||||
GSTT1 | – | Deletion | – | – | ||||
GSTA1 | rs3957357 | −69C/T | 0.38 | 0.25 | 0.62 | 0.40 | 1.19 | 0.26 |
GSTP1 | rs1695 | 562A/G/exon 5, Ile105Val | 0.30 | 0.91 | 0.34 | 0.33 | 0.17 | 0.68 |
SOD2 | rs4880 | −9C/T/exon 1, Ala16Val | 0.47 | 2.22 | 0.14 | 0.51 | 4.82 | 0.03 |
NRF2 | rs6721961 | −617C/A | 0.12 | 0.17 | 0.68 | 0.12 | 1.41 | 0.24 |
adbSNP from http://www.ncbi.nlm.nih.gov/projects/SNP
b MAF minor allele frequency
cTest of departure from HWE