Table 3.
Effects of CBE and indomethacin on carrageenan-induced hind paw edema in rats (n = 6).
| Treatment | Edema volume (mL) | |||||
|---|---|---|---|---|---|---|
| 1st h | % EI | 3rd h | % EI | 5th h | % EI | |
| 80% Tween | 0.36 ± 0.05 | — | 0.83 ± 0.05 | — | 0.74 ± 0.03 | — |
| CBE 100 mg/kg | 0.18 ± 0.02 | 51.61 | 0.55 ± 0.03∗ | 33.78 | 0.57 ± 0.06 | 22.58 |
| CBE 250 mg/kg | 0.14 ± 0.02∗∗ | 60.64 | 0.45 ± 0.03∗ | 45.60 | 0.49 ± 0.06∗ | 34.28 |
| CBE 500 mg/kg | 0.12 ± 0.03∗∗ | 66.00 | 0.41 ± 0.07∗ | 50.37 | 0.40 ± 0.05∗ | 46.06 |
| Indomethacin 10 mg/kg | 0.06 ± 0.03∗∗ | 82.39 | 0.25 ± 0.02∗∗ | 70.32 | 0.31 ± 0.04∗∗ | 58.36 |
Results are mean of edema volume ± S.E.M. % EI is percentage of edema volume inhibition of test compound. ∗P < 0.05 and ∗∗P ≤ 0.01 compared with control group.