Table 1. Comparison 1: amantadine versus placebo: money spent on cocaine per week (skewed data).
Study | Outcome | Experimental group (n=8 randomised) (n=3 completed) | Control group (n=4 randomised) (n=3 completed) | Statistic |
---|---|---|---|---|
Leal 1994 | mean $ per week spent on cocaine; at week 1 | 162 (SD 138) | 70 (SD 29) | none available (see note 1) |
Leal 1994 | mean $ per week spent on cocaine; at week 6 | 115 (SD 127) | 32 (SD 33) | none available (see note 1) |
Leal 1994 | mean $ per week spent on cocaine; at week 12 | 70 (SD 63) | 59 (SD 64) | none available (see note 1) |
SD = standard deviation
1. trial investigators report no statistical analysis that compares amantadine and control groups, although they note that “the AsPD patients were spending significantly more money on drugs than the non-AsPD patients at weeks 1 and 6” (page 33, col 2).