Table 12. Comparison 3: desipramine versus placebo: urine toxicology (cocaine metabolite).

Study	Outcome (see note 1)	Experimental group (n=17 completed)	Control group (n=12 completed)	Statistic
Arndt 1994	mean % cocaine-positive urinalysis results: across all 12 weeks of the study	78%	77%	favours neither condition (ANOVA carried out by trial investigators showed no indication of treatment group effect; F<1.0, P>0. 10) (see note 2)

1. urinalyses performed twice-weekly throughout study and evaluated for cocaine metabolite (benzoylcognine); urine samples collected on a random schedule.

2. investigators report that “the AsPD subjects showed no indication of either a medication group effect (F<1.0, P>0.10) or a decrease in the proportion of cocaine-positive urines over time (F<1.0, P>.010)” (page 155, col 2)