Table 13. Comparison 3: desipramine versus placebo: substance misuse.
Study | Outcome (see note 1) | Experimental group (n=17 completed) | Control group (n=12 completed) | Statistic (see note 2) |
---|---|---|---|---|
Arndt 1994 | ASI drug factor scores | 0.259 | 0.234 | favours neither condition (P>0.05) |
Arndt 1994 | days opiate use | 2 | 2 | favours neither condition (P>0.05) |
Arndt 1994 | days cocaine use | 9 | 8 | favours neither condition (P>0.05) |
Arndt 1994 | cocaine craving score | 8 | 7 | favours neither condition (P>0.05) |
ASI = Addiction Severity Index
1. 12-week end of treatment means; ASI factor scores range from 0 to 1 with larger values indicating greater problem severity
2. between-groups ANCOVA using baseline value as covariate; baseline values reflect the 30 days before start of treatment; analysis carried out by trial investigators