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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Aug 4;(8):CD007667. doi: 10.1002/14651858.CD007667.pub2

Table 13. Comparison 3: desipramine versus placebo: substance misuse.

Study Outcome (see note 1) Experimental group (n=17 completed) Control group (n=12 completed) Statistic (see note 2)
Arndt 1994 ASI drug factor scores 0.259 0.234 favours neither condition (P>0.05)
Arndt 1994 days opiate use 2 2 favours neither condition (P>0.05)
Arndt 1994 days cocaine use 9 8 favours neither condition (P>0.05)
Arndt 1994 cocaine craving score 8 7 favours neither condition (P>0.05)

ASI = Addiction Severity Index

1. 12-week end of treatment means; ASI factor scores range from 0 to 1 with larger values indicating greater problem severity

2. between-groups ANCOVA using baseline value as covariate; baseline values reflect the 30 days before start of treatment; analysis carried out by trial investigators