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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Aug 4;(8):CD007667. doi: 10.1002/14651858.CD007667.pub2

Table 23. Comparison 6: phenytoin versus placebo: anger-hostility (skewed data).

Study outcome n(Exp) mean(Exp) SD(Exp) n(Cntrl) mean(Cntrl) SD(Cntrl) statistic notes
Barratt 1997
300 mg/day		 POMS anger-hostility sub-scale; impulsive subgroup; at 6 weeks 30 20.4 no data 30 22.3 no data Scores not significantly reduced from baseline (ANOVA, Geissner-Greenhouse adjusted; no further details given) Favours neither condition (impulsive aggression subgroup)
Barratt 1997
300 mg/day		 POMS anger-hostility sub-scale; non-impulsive subgroup; at 6 weeks 30 11.2 no data 30 12.5 no data Scores not significantly reduced from baseline (ANOVA, Geissner-Greenhouse adjusted; no further details given) Favours neither condition (non-impulsive aggression subgroup)

POMS = Profile of Mood States; SD = standard deviation