Methods | Randomisation by sealed envelopes. | |
Participants | Nearly all women in that geographical area, including those with ‘high-risk’ pregnancies. Recruitment 1979-1981. 1628 women | |
Interventions | Routine ultrasound examination at 18 weeks (biparietal diameter measured) and 32 weeks (biparietal diameter and mean abdominal diameter) with additional examination at 36 weeks’ gestation if fetus small-for-gestational age and/or presenting by breech - versus selective examination for clinical indications only | |
Outcomes | Obstetric interventions (antepartum and intrapartum) for singleton pregnancies only. Perinatal outcome indices for all pregnancies (including multiple pregnancies) | |
Notes | This trial was reported in letter form only in 1984. It subsequently became clear that there were inconsistencies in results, and the data were subsequently re-analysed. The data entered in this review are derived from more recent unpublished and published reports | |
Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Unclear | Not stated. |
Allocation concealment? | Unclear | Described as “sealed envelope”. |
Blinding? Women |
No | Not feasible. |
Blinding? Clinical staff |
No | Not feasible. |
Blinding? Outcome assessors |
No | Not feasible. |
Incomplete outcome data addressed? All outcomes |
Yes | The data could be re-included. |
Free of selective reporting? | Yes | Selective outcome reporting bias not apparent. |
Free of other bias? | No | More smokers in screened group; historical study. |