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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: Cochrane Database Syst Rev. 2008 Oct 8;(4):CD001451. doi: 10.1002/14651858.CD001451.pub3
Methods Randomised by women selecting one of a number of envelopes (< 6) containing a computer-generated random 1 or 2 and a study number
Participants All pregnant women who attended antenatal clinic < 24 weeks’ gestation, i.e. unselected population. Multiple pregancies excluded once diagnosed (and study numbers reused). 1527 women
Interventions All women had a dating scan 16-24 weeks’ gestation. Study group had a further scan at 32-36 weeks’ gestation (ideally 34 weeks’ gestation) which aimed to detect small-for-gestational-age fetuses, and if estimated fetal weight fell below the 20th centile for gestation, this was reported and additional scans recommended but not arranged. Clinicians were able to order further scans for the control group if clinically indicated
Outcomes Mainly perinatal outcome indices. Number of further ultrasound scans
Notes Scan to detect small-for-gestational age.
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Unclear Described as “randomised controlled trial”.
Allocation concealment? Unclear Not stated.
Blinding?
Women
No Not feasible.
Blinding?
Clinical staff
No Not feasible.
Blinding?
Outcome assessors
No Not feasible.
Incomplete outcome data addressed?
All outcomes
Unclear Not stated.
Free of selective reporting? Unclear No information provided.
Free of other bias? Unclear No information provided.