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. 2014 Sep 11;4:6281. doi: 10.1038/srep06281

Table 3. False-Positive Report Probability Values for associations between ESCC risk and genotypes of ERCC2 polymorphisms.

             Prior probability
Genotypes Positive OR (95% CI) a P value b Statistical Power c 0.2500 0.1000 0.0100 0.0010 0.0001
rs238406                
TT vs. GG 1.24 (0.98–1.57) 0.075 0.988 0.185 0.406 0.883 0.987 0.999
TG/TT vs. GG 1.24 (1.04–1.49) 0.017 0.975 0.050 0.136 0.633 0.946 0.994
Pack-years > 16 1.49 (1.12–1.98) 0.006 0.523 0.033 0.094 0.532 0.920 0.991
Combined risk genotypes                
No. at-risk genotypes d                
1 vs. 0 1.25 (1.03–1.52) 0.026 0.984 0.073 0.192 0.723 0.964 0.996
2 vs. 0 1.62 (1.16–2.26) 0.005 0.452 0.032 0.091 0.523 0.917 0.991
≥1 vs. 0 1.28 (1.06–1.56) 0.011 0.930 0.034 0.096 0.539 0.922 0.992

aThe crude OR reported in Tables 2 and 3.

bThe omnibus chi-square test of the genotype frequency distributions reported in Tables 2 and 3.

cStatistical power was calculated using the number of observations in the study and the OR and P values in Tables 2 and 3.

dCombined risk genotypes were to referred to ERCC2 rs238406 TG/TT + rs13181 TG/GG.