Figure 6.
mMSC co-localize with subcutaneous, syngeneic 4T1 murine breast carcinoma. 4T1 cells were subcutaneously injected into the hind limbs of Balb/C mice (n=5). 10 days post tumor establishment, mMSC-ffLuc were IV injected. (A) Mice were imaged 0.5, 6 and 12 days post mMSC-ffLuc injection for rLuc (tumor) and ffLuc (mMSC) activities, demonstrating co-localization at days 6 and 12. (B) IHC on 4T1 tumor sections revealed incorporation of ffLuc+MSC.