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. Author manuscript; available in PMC: 2014 Sep 11.
Published in final edited form as: Genes Brain Behav. 2011 Aug 15;10(7):805–816. doi: 10.1111/j.1601-183X.2011.00720.x

Figure 7. Female NR2B deficient mice have a more rapid clearance of high dose ethanol.

Figure 7

To determine if NR2B deficient (KO) mice metabolize ethanol at a different rate than control littermates, mice from each of the genotypes were injected with 1.5 and 4.0 g/kg ethanol (i.p.) and blood samples were taken at various times. Overall there were no differences in the clearance rate of ethanol between the genotypes. Only the female KO mice had a steeper slope (i.e., more rapid clearance rate of high dose ethanol) than control littermates. There were no differences in slope or intercept for any of the genotypes at the low ethanol dose. Sample sizes = 12/genotype except CAM females = 3.