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. 2014 Jun 23;5(9):983–988. doi: 10.1021/ml500156v

Table 3. Analgesic Activity of the Mutual Prodrugsa.

  no. of writhings per 20 min ± SE % protection
control 62 ± 0.6 0
PP 34 ± 0.9 45
IB 25 ± 0.6 60
IB–MP 3 ± 0.4 95
DIC 23 ± 5 63
DIC–MP 8 ± 2 87
KET 21 ± 4 66
KET–MP 17 ± 5 73
BET–MP 34 ± 0.9 45
a

No. of writhings values were obtained by averaging three independent trials; data represent the mean ± SE.