Figure 3.

PN-FLX treatment alters dendritic morphology of IL pyramidal neurons. A–D, IL neurons from PN-FLX mice have significantly less complex apical dendritic trees, relative to controls, as evidenced by a decrease in the number of intersections (A), number of nodes (B), and dendritic material (C), with no overall decrease in average apical arbor length (D). E, Decreased complexity was most pronounced in the proximal to medial region of the soma. F, A schematic of altered dendritic morphology. N = 3 mice/group; N values for cells per condition are indicated in the figure. *p < 0.05; **p < 0.01.