Table 1.

Experimental cohort used to narrow down the 5-HT-sensitive developmental time window

Experimental cohort	Treatment	Time	Animals	Males	Females	Litter	Mice per litter	Male mice per litter	Female mice per litter	Females/total
Sensitive period, OF, NSF, SESC (Fig. 1)	VEH	P2–P21	20	10	10	A	6	3	3	0.50
	VEH	P2–P21				B	5	2	3	0.60
	VEH	P2–P21				C	5	2	3	0.60
	VEH	P2–P21				D	4	1	3	0.75
	FLX	P2–P21	20	11	9	A	6	4	2	0.33
	FLX	P2–P21				B	5	5	0	0.00
	FLX	P2–P21				C	4	1	3	0.75
	FLX	P2–P21				D	5	1	4	0.80
	VEH	P2–P11	24	12	12	A	6	2	4	0.67
	VEH	P2–P11				B	6	3	3	0.50
	VEH	P2–P11				C	6	3	3	0.50
	VEH	P2–P11				D	6	4	2	0.33
	FLX	P2–P11	23	11	12	A	5	2	3	0.60
	FLX	P2–P11				B	5	2	3	0.60
	FLX	P2–P11				C	4	3	1	0.25
	FLX	P2–P11				D	5	3	2	0.40
	FLX	P2–P11				E	4	1	3	0.75
	VEH	P12–P21	19	11	8	A	5	1	4	0.80
	VEH	P12–P21				B	6	4	2	0.33
	VEH	P12–P21				C	5	4	1	0.20
	VEH	P12–P21				D	4	3	1	0.25
	FLX	P12–P21	23	11	12	A	8	3	5	0.63
	FLX	P12–P21				B	5	2	3	0.60
	FLX	P12–P21				C	6	3	3	0.50
	FLX	P12–P21				D	3	2	1	0.33
	VEH	P22–P41	19	12	7	A	7	3	4	0.57
	VEH	P22–P41				B	6	5	1	0.17
	VEH	P22–P41				C	6	4	2	0.33
	FLX	P22–P41	24	13	11	A	7	4	3	0.43
	FLX	P22–P41				B	7	3	4	0.57
	FLX	P22–P41				C	5	3	2	0.40
	FLX	P22–P41				D	5	3	2	0.40
	Total		172	91	81	32	172	89	83
						Average litter size:	5.4		Average sex composition:	0.48