Table 2.

Overview of experimental cohorts used to study the P2–P11 period and the effect of mPFC lesions

Experimental cohort	Treatment	Time	Animals	Males	Females	Litter	Mice per litter	Females/total
Naive controls			26	15	11	5	5.2	0.42
Sucrose preference (Fig. 2)	VEH	P2–P11	23	14	9	5	4.6	0.39
	FLX	P2–P11	22	12	10	5	4.4	0.45
FST (Fig. 2)	VEH	P2–P11	15 (23)	9 (14)	6 (9)	5	3.0 (4.6)	0.39
	FLX	P2–P11	10 (22)	5 (12)	5 (10)	5	2.0 (4.4)	0.45
Dendritic morphology (Fig. 3, Table 1)	VEH	P2–P11	3 (15)	3 (7)	0 (8)	3	1.0 (5.0)	0.53
	FLX	P2–P11	3 (14)	3 (7)	0 (7)	3	1.0 (4.7)	0.50
Electrophysiology (Figs. 4, 5, Table 2)	VEH	P2–P11	10 (27)	10 (14)	0 (13)	5	2.0 (5.4)	0.48
	FLX	P2–P11	10 (25)	10 (12)	0 (13)	5	2.0 (5.0)	0.52
Fear conditioning (Fig. 6)	VEH	P2–P11	24 (34)	14	10 (20)	7	3.4 (4.9)	0.59
	FLX	P2–P11	25 (32)	17	8 (15)	6	4.2 (5.3)	0.47
IL lesion (Fig. 7)	Sham	Adulthood	27	20	7
	Ibotenic acid	Adulthood	24	16	8
PL lesion (Fig. 8)	Sham	Adulthood	21	21	0
	Ibotenic acid	Adulthood	23	23	0

Numbers in parentheses refer to animals generated and are shown if only a subset of these animals were used in experiments.