Table 5.
Intrinsic properties of pyramidal neurons in the IL and PL regions of adult PN-FLX and PN-VEH mice
| Vm (mV) | Spike amplitude (mV) | Rin (MΩ) | Cm (pF) | Rheobase (pA) | |
|---|---|---|---|---|---|
| IL layer II/III | |||||
| Saline (n = 13) | −85.5 ± 2.8 | 87.3 ± 1.5 | 165.0 ± 25.9 | 86.5 ± 5.0 | 134 ± 26 |
| Fluoxetine (n = 19) | −83.6 ± 1.8 | 84.9 ± 1.2 | 130.9 ± 13.2 | 91.6 ± 9.0 | 150 ± 16 (n = 17) |
| p value | 0.6 | 0.2 | 0.2 | 0.7 | 0.6 |
| PL layer II/III | |||||
| Saline (n = 10) | −86.6 ± 2.4 | 88.5 ± 1.1 | 77.9 ± 15.4 | 99.8 ± 7.5 | 255 ± 31 |
| Fluoxetine (n = 20) | −88.9 ± 1.6 | 83.7 ± 1.4 | 115.7 ± 13.7 | 87.1 ± 4.9 | 173 ± 21 (n = 17) |
| p value | 0.4 | 0.04* | 0.1 | 0.1 | 0.03* |
Data are mean ± SEM. Vm, Resting membrane potential; spike amplitude in mV; Rin, input resistance; Cm, membrane capacitance. N values are indicated in the table.
*p < 0.05.