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. 2014 Sep 10;34(37):12470–12480. doi: 10.1523/JNEUROSCI.0542-14.2014

Figure 1.

Figure 1.

Cytokine expression in dorsal hippocampus after systemic LPS administration. Mean fold increase (±SEM) in mRNA expression relative to actin and home-cage control subjects (n = 4) for proinflammatory cytokines in dorsal hippocampus 3, 6, or 9 h after intraperitoneal injections of SAL or LPS (n = 3 per group). a, There was a robust increase in IL-1β mRNA expression in dorsal hippocampus after LPS administration 3 and 6 h after injection but not 9 h later. b, TNF-α mRNA levels were significantly elevated in LPS compared with SAL subjects only at the 6 h time point. c, Similar to IL-1β, IL-6 mRNA expression in dorsal hippocampus was significantly higher in LPS-treated rats 3 and 6 h after injection but not 9 h later. *p < 0.05.