Methods	Randomised, double blind, active control, cross-over (two 2 week periods - washout?). No follow up. Not enriched
Participants	Trigeminal neuralgia. N = 12 Age 41-78 years. Male 5, Female 7.
Interventions	CBZ to maximum tolerated dose Tocainide 20 mg/kg in 3 divided daily doses. Actual doses not reported
Outcomes	TN score consisted of severity, frequency and duration of attacks
Notes	Oxford Quality Score: R = 1, DB = 1, W = 0, Total = 2 Sponsored by Folsam Research Foundaton, Vivian L Smith Foundation
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	‘randomised double blind technique’
Allocation concealment (selection bias)	Unclear risk	Not stated
Blinding (performance bias and detection bias) Active and controlled appeared similar	Unclear risk	Stated as double blind but no further information
Duration	High risk	2 week treatment
Outcome	Low risk	Individual start and end pain scores given
Incomple outcome assessment	Unclear risk	Not stated
Size	High risk	group size below 50