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Excision of N7- and O2- pyridyloxobutyl (POB) base adducts by AlkD. a, Chemical structures of N7-POB-deoxyguanine and O2-POB-deoxycytosine. b,c, Time courses for the release of N7-POB-dG (black squares) and O2-POB-dC (red circles) in the presence (closed symbols, solid lines) and absence (open symbols, dashed lines) of Bacillus cereus AlkD (b) or human AAG (c). Error bars represent the standard deviation from three independent measurements.
