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. 2010 Apr 14;2010(4):CD008099. doi: 10.1002/14651858.CD008099.pub2

Bentley 1987.

Methods R, DB, 4 parallel groups. Single oral dose
Medication administered when baseline pain reached moderate to severe intensity
Pain assessed at baseline then hourly up to 5 hours
Participants Oral surgery involving impacted tooth or removal of bone
N = 128 (120 analysed for efficacy)
M = 46, F = 74
Mean age 25 years
Interventions Codeine 60 mg, n = 21
Paracetamol 1000 mg, n = 41
Paracetamol + codeine 1000/60 mg, n = 41
Placebo, n = 17
Outcomes PI: non‐standard 10 point scale
PR: standard 5 point scale
PGE: standard 5 point scale
Use of rescue medication
Adverse events
Withdrawals
Notes Oxford Qualtiy Score: R1, DB1, W1. Total = 3
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Not described
Allocation concealment? Unclear risk Not described
Blinding? 
 All outcomes Unclear risk Not described