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. 2010 Apr 14;2010(4):CD008099. doi: 10.1002/14651858.CD008099.pub2

Honig 1984.

Methods Randomised, double blind, 4 parallel groups. Single oral dose
Medication administered when baseline pain reached a moderate to severe intensity
Pain assessed at 0, 30, 60 mins, then hourly to 6 hours
Participants Various elective surgical procedures, including orthopaedic, abdominal and thoracic
N = 116
M = 71, F = 45
Mean age 45 years
Interventions Codeine 60 mg, n = 28
Paracetamol 600 mg, n = 28
Paracetamol + codeine 600/60 mg, n = 30
Placebo, n = 30
Outcomes PI: standard 4 point scale
PR: standard 5 point scale
PGE: standard 5 point scale
Use of rescue medication
Adverse events: any, serious
Withdrawals
Notes Oxford Qualtiy Score: R1, DB2, W0. Total = 3
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Not described
Allocation concealment? Unclear risk Not described
Blinding? 
 All outcomes Low risk "Capsules were identical in appearance"