Jain 1988.
Methods | Randomised, double blind, 4 parallel groups. Single oral dose Medication administered when baseline pain reached a moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly to 8 hours |
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Participants | Various surgical procedures, mostly Cesarian section and common gynaecological operations N = 161 M = 29, F = 132 Mean age 29 years |
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Interventions | Codeine 60 mg, n = 40 Diflunisal 500 mg, n = 41 Diflunisal/codeine 500/60 mg, n = 40 Placebo, n = 40 |
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Outcomes | PI: standard 4 point scale PR: standard 5 point scale PGE: standard 5 point scale Use of rescue medication Adverse events: any, serious Withdrawals |
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Notes | Oxford Qualtiy Score: R1, DB1, W1. Total = 3 No details about timing of rescue medication |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | Not described |
Allocation concealment? | Unclear risk | Not described |
Blinding? All outcomes | Unclear risk | Not described |